Doing work on Ri’s subdivisions today 

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“Doing what you think is right can stem from a world all wrong”

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Amygdala is a world that is wrong in every way 

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From my anger over this world I bring to you a new world… Organelle 

A world with the goal of evolution, with characters from a series of Darwinist logic, looking at biology differently with hopes to create something amazing 

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What is Critical Fiction?

Crit-Fic is basically fan fiction with the exception that it’s based on a work that disappointed me. For a while I was a fan of Sam Fennah’s work. I watched and shared his animations, enjoyed his web series Satellite City and waited patiently to finally get his first book Amygdala… just to hate it

To the point of being offended at it!

I’m not as harsh as others who were critical of this work. I found the character animations very creative but Amygdala, I consider bad taste and I wouldn’t recommend this book to anyone

I however still love the characters and I’m borrowing them for my world building project. The name of my world is Organelle and it’s all based on biology 

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I’m not the only one to feel this way

“While I usually appreciate a good moral dilemma, (in this case, an argument between pushing for a merciful society, or remaining in pure Darwinistic logic), the arguments presented in the book left me vehemently disagreeing with both sides. I believe this must have been intentional, but it became problematic when the primary characters, including Lucy, aligned strongly with these extremes.”

“my frustration peaked during a major public debate in the last third of the book, when both sides of the argument were spearheaded by major political leaders. In particular, I felt the arguments presented in favor of a more merciful society felt surprisingly childish, considering that the one making it was supposedly an intelligent and capable leader; it felt like she was intentionally lobotomized, just so she would lose.”

“I did not enjoy this.The plot is poorly thought out, the characters are quite bland, there are way too many characters to keep up with, it takes too long to get going, the worldbuilding, while interesting, is a bit too off-putting for my taste, and the themes are just terrible and poorly constructed.”

  “Fennah is careful to admit at the fore of the book his desire to explore conflicting ideologies, but too much weight is placed on one side of this argument for this to ring particularly true. At the same time as characters lovingly espouse the merits of quite literally eating children versus a rudimentary form of healthcare”

“Abysmal. Objectively bad writing. Lucy Lacemaker has so much plot armor, she might as well be piloting a mech.”

“I really hope Fennah learns from this and grows as an author. There is potential in this. He just needs to scrutinize his stories a bit harder next time to iron out all these problems.”

If you’re wondering what I did with my copy of Amygdala, I cut out the pictures of my favourite characters and threw the book away. It’s in a landfill now 

Despite all of this I still love these characters and so I’m creating a world where I can experience them in a different light than what Fennah has for them. I will not be reading any more of his books and I hold nothing against him as a person nor do I make any money off of this project. I just have a different vision for the characters and a desire to share my world 

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A bit of world building is what I plan to do 

Each nation is built following the Cosmic Wheel which is made of circular mitochondrial DNA 

The elite of Organelle have a hypothesis that DNA holds answers to life’s mysteries

-ˋˏ ༻ O ༺ ˎˊ-

The people of Organelle do not think in the same way as humans with the exception that there are docile and hostile personality types

Docile personality types:

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Type 1 (Totipotent):

Totipotent cells undergo zygotic genome activation

essential for the ensuing first lineage decisions and the overall progression of embryonic development

The first lineage of anything in life is believed to be the most telling, so therefore these people have trained themselves to actively search for the first lineage of information, and to judge it as it began instead of what it has later become. They use the example of a small child being the most pure as a means to determine the quality of all things. Another example of this would be if there was a news report, only the first initial report is listened to everything afterwards has been corrupted. If you’re asked a question and you pause for too long then your answer is silence and no need to listen to what you have to say after a long pause. If you were to prepare a speech, they would not listen, and for a politician to read from a teleprompter is unacceptable and they will not listen to any of it because there was time for it to be corrupted

ZGA involves the activation of the zygotic genome, leading to the transcription of genes that were previously silent

DNA, the molecule that stores genetic information, acts as a template

a single-stranded nucleic acid (DNA or RNA) that serves as a guide for the synthesis of a new DNA, RNA, or protein molecule during processes like replication, transcription, and translation

the process where a cell creates an RNA copy of a DNA sequence, forming a messenger RNA (mRNA) molecule

It is believed that in all things there is only one strand of truth. It is believed that this one strand is a guide for the creation and understanding of new information. The “strand of truth” is what is believed to me the message in the conversation 

Totipotent cells undergo changes in DNA methylation

DNA methylation is an epigenetic process where methyl groups are added to DNA, which can alter gene expression by influencing how tightly DNA is packed and regulating which genes are transcribed

Epigenetics refers to how your behaviors and environment can cause changes that affect the way your genes work

Ones behaviour and environment makes a person who they are publicly but also influence their mind and their heart. It is important to take the steps to change their behaviour and seek control over their environment, either through adaptation to that environment or to influence it to change if it is unacceptable 

a chemical group consisting of one carbon atom bonded to three hydrogen atoms

Methyl groups are generally very stable and unreactive

Type 1 personalities are generally calm and not overly aggressive in situations unless the situation calls for such behaviour. One thing however, is they consider the idea that if you’re someone who is different you should try to bond with the majority 

histone modifications

chemical changes to histone proteins that can alter chromatin structure and regulate gene activity

Histones are basic proteins, meaning they have a high concentration of positively charged amino acids

Examples are:

lysine (Lys, K)

potentially supporting the immune system

Type one personalities are pro military and police force and are in support of fighting for the sake of the species 

arginine (Arg, R)

is necessary for making proteins and is commonly used for circulation. L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow

It is someone’s right to travel down their path in life, freedom of choice and freedom of location if where they are currently is unacceptable 

and histidine (His, H)

Histidine's unique imidazole side chain allows it to participate in enzyme catalysis and metal ion binding

histidine can function as either a general acid catalyst or a general base catalyst

Adaptability is important so that a being can adjust to two different takes on a situation. To see a situation from both sides and act accordingly

Acid:

the rate of the catalyzed reaction is dependent on the concentration of all acids present, not just hydronium ions, and the acids are unchanged by the overall reaction

They understand that beings naturally participate in groupthink, while adaptation is important, someone who only follows groupthink is not a contributing member of society 

Base:

The positively charged histones bind to the negatively charged DNA, forming complexes called nucleosomes

Nucleosomes are what is created when DNA wraps around histones 

It is understood that people naturally gravitate towards information they find pleasant and deny what is inconvenient to them. For a type one accepting a hard truth is a process 

and chromatin remodeling

a dynamic process where chromatin, the DNA-protein complex, is rearranged to allow access of regulatory proteins, like transcription factors, to DNA, thereby controlling gene expression

A DNA-protein complex is a structure formed when proteins, like transcription factors or histones, bind to DNA

regulatory proteins are controlling gene expression by either activating or repressing transcription

It is understood that when releasing hard truths type one believe it should be done through the process of “activating” by releasing a detail and “repressing” by holding back a detail. The process they believe creates more information as you prepare a society for disclosure 

The same process is used to bring about social change 

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Type 2 (Pluripotent):

Pluripotent stem cells can differentiate into the ectoderm, mesoderm, and endoderm, which can give rise to all cell types

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Type 3 (Multipotent):

unspecialized meaning they have not yet “decided” what type of adult cell they will be. They can self-renew and make two new stem cell. They can differentiate to make multiple types of cells

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Type 4 (Oligopotent):

Oligopotent stem cells have a more restricted differentiation potential than multipotent or pluripotent stem cells

Oligopotent stem cells can differentiate into cells of the blood and immune systems. For example, myeloblast stem cells produce white blood cells, and lymphoid stem cells differentiate into lymphocyte

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Type 5 (Unipotent):

Unipotent stem cells can only differentiate into one cell type

Unipotent stem cells are found in adult organ tissues that are dedicated to a specific cell lineage

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Hostile Personalities:

Type 6 (Innate immunity):

Innate immunity acts quickly, within minutes to hours, upon encountering a pathogen

It doesn't distinguish between different types of pathogens, responding the same way to all foreign invaders

Unlike adaptive immunity, innate immunity doesn't "remember" past encounters, so the response is the same regardless of prior exposure

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Type 7 (Adaptive immunity):

Adaptive immune responses are highly targeted, recognizing and responding to specific antigens (foreign substances)

The adaptive immune system can recognize and respond to a vast array of different antigens

After encountering a pathogen, the adaptive immune system "remembers" it, allowing for a faster and more robust response upon re-exposure

Unlike the innate immune system, which responds rapidly, adaptive immunity takes time to develop a specific response

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Type 8 (Autoimmunity):

Normally, the immune system defends the body against foreign invaders like bacteria and viruses. In autoimmunity, this system malfunctions and targets the body's own tissues as foreign

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Type 9 (Humoral immunity):

is characterized by the production of antibodies by B cells to fight against pathogens in the body's extracellular fluids, neutralizing them and marking them for destruction

Humoral immunity primarily protects against extracellular pathogens, such as bacteria and toxins, that are circulating in the body fluid

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Type 10 (Cell-mediated immunity):

Unlike humoral immunity, cell-mediated immunity doesn't involve antibodies; instead, it relies on the direct action of T cells and other immune cells

The process begins with the activation of naive T cells by antigen-presenting cells (APCs) that display fragments of antigens (epitopes) on their surface, using MHC molecules

Helper T cells (Th cells) play a vital role in coordinating the immune response, including activating other T cells and B cells

Cell-mediated immunity also involves the activation of macrophages, which can engulf and destroy intracellular pathogens

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I’m creating different personalities so that there can be some surprising reactions from the people